Call of Cthulhu: Dark Corners of the Earth is a video game released in 2005 for the Xbox and 2006 for PC, developed by Headfirst Productions and published by Bethesda Softworks. The game is based-off the Call of Cthulhu role-playing game by Chaosium and is a reminagning of the novella The Shadow Over Innsmouth.
The main character is Jack Walters and the Ichthyosis condition is part of the game. The Majority of the plot takes place in the seaside town of Innsmouth, Massachusetts. Jack goes to Innsmouth to solve a missing person case. He encounters the Esoteric Order of Dagon and their idols of worship. He eventually learns the truth about himself and some of the things that live in the dark corners of the earth.